Metagenics - Kaprex - 60 Softgels

IndIcatIons and Usage Kaprex is indicated for individuals with minor pain. Kaprex offers a safer approach and has been recommended for daily use with no serious adverse events reported.* Established protein and genomic testing technologies and clinical evaluations demonstrate that Kaprex ingredients offer a high level of comparable efficacy with a leading competitor. These ingredients have been shown to be active in target tissues (e.g., joint) while exhibiting minimal activity in non-target tissues (e.g., gastrointestinal), making it an effective approach with a reduced risk of adverse events. It works by interfering with signals in the body that initiate the production of compounds that may negatively impact cartilage and other joint tissues.* descrIptIon Kaprex (in a dark, oblong softgel delivery form) is a dietary supplement formulated with a modified hops extract that has been demonstrated to modulate specific kinases associated with minor pain. Kinases function to chemically modify other proteins and help regulate eicosanoids (e.g., COX-2, PGE2), cytokines (e.g., TNF-a), reactive oxygen species (nitric oxide), and other mediators (e.g., NF-kB) that may negatively impact the body both locally and systemically. Research suggests kinase modulation is an attractive approach to target the origins of minor pain.* 1-3 Kaprex effectively calms the body's eicosanoid cascade by modulating enzyme formation in cells associated with minor pain. It does so without directly blocking constitutive (housekeeping) cyclooxygenase (COX) enzyme activity, a mechanism known to cause adverse effects with long-term use in some individuals. Instead, Kaprex indirectly modulates induced COX-2 proteins activated in response to stimuli.* Kaprex and its primary active ingredients have been the subjects of proprietary cell proteomic research, safety evaluations, human ex vivo research, and human clinical research to help determine efficacy, bioavailability.