Carnispan Timed Release L-Carnitine Fumarate (880mg 60 Tablets)

New Carnispan® from Tishcon Corp. is a high-dose L-Carnitine dietary supplement that delivers 500mg of elemental carnitine in a Timed Release formulation specifically designed to spread the benefits of Carnitine over a longer period of time. Carnispan® is 100% vegetarian.Suggested adult dosage is one 500mg tablet with a meal up to twice per day or as recommended by your healthcare professional. L-Carnitine Fumarate is a stable form of L-Carnitine. Each serving size of 1 tablet provides 880 mg of L-Carnitine Fumarate which delivers 500 mg of elemental Carnitine. L-Carnitine has important metabolic functions and is believed to perform crucial roles in cardiovascular metabolism, exercise performance, weight control, maternal and infant nutrition and more. L-Carnitine plays a very important role in fat metabolism. It is essential for transporting long-chain fatty acid molecules (acylCoA) from the cytosol into the mitochondria of cells in the form of acylcarnitine. The aylcarnitine is then shuttled across the inner mitochondrlal membrane where it is reconjugated to form acylCoA. The free carnitine molecule is then shuttled back to pick up another acyl moiety. This specialized transport mechanism which is tightly regulated is known as the "carnitine shuttle". Thus carnitine supplies the necessary fuel for oxidation in the electron transport chain to produce vital biological energy as ATP (adenosine triphosphate). Carnitine is also involved in the formation of acylcarnitine from activated short-chain fatty acids (acylCoA) and thus protect against the accumulation of acylCoA that may be deleterious to the cell. Carnitine has also been shown to augment the aerobic metabolism of carbohydrates and enhance oxidative phosphorylation (Schonekess et al, 1995).