DHEA 50mg (Dehydropiandrosterone)
Product Description
DHEA is a natural steroid hormone that is synthesized
from cholesterol through pregnenolone by the adrenal
glands. DHEA acts as an antagonist for glucocorticosteroid
hormones and is the parent precursor for other important
steroid hormones, such as estradiol and other estrogens, and
testosterone. While not a precursor to progesterone, DHEA
can indirectly influence progesterone synthesis through a
feedback mechanism whereby pregnenolone is converted
to progesterone based on DHEA levels. Apart from these
functions, DHEA also has important biological functions itself.
Recent experimental and human studies show that DHEA
is involved in a large variety of physiological processes,
including immune function, brain function, bone metabolism,
blood lipid metabolism, energy metabolism, the regulation of
normal blood sugar and insulin levels, and the maintenance of
lean body mass. DHEA and its metabolite DHEA sulfate are
present in human adult plasma in concentrations of 0.01-0.02
μM and 5 to 7 μM, respectively. DHEA sulfate levels are low
in early childhood, begin to rise after age 7, peak at age 20-24,
and then drop at a rate of approximately 20% per decade, until
at age 85-90, levels are 10-15% of what they used to be at age
20-30. DHEA levels also decline under a variety of conditions
of physiological stress, such as acute and chronic infections,
and trauma. Vegetarians have been shown to have decreased
DHEA levels as well.
