Jarrow Formulas Bone-Up (Vegetarian), 120 Count
Product Description
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The human skeleton contains at least 270 distinct bones at birth. By adulthood, the number shrinks to 206 as young bones fuse and grow together. Yet even after reaching maturity, the skeleton is continually "remodeled" throughout life. The number of bones may no longer change, but what remains is just as dynamic.
Promotes bone density with comprehensive supplemental nutrition.
Provides the essentials for proper calcium utilization by the body.
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Between 2 - 4 percent of the skeleton is normally broken-down and rebuilt each year in an ongoing dance between osteoclasts (bone breaking cells) and osteoblasts (bone building cells). With age, however, bone-resorption and bone-building can fall out of balance. This is especially true in women who typically lose 30 percent of their skeletal density between ages 45 and 75 as estrogen levels change. Yet in men, those same decades often result in a 15 percent loss. And despite the negative effects becoming noticeable with age, it's clear that what we do for our bones along the way greatly impacts how they will fare down the road.*
Calcium: Just a Start
The average adult skeleton amounts to roughly 14 percent of total body-weight, with 1,000 - 1,200 grams being calcium alone. Undoubtedly calcium is important. Nevertheless, research indicates that 85 percent of women over the age of 20 and 50 percent of men over 35 consume less than the Recommended Daily Intake (RDI) for calcium. Making matters worse is diets high in sugar, protein, caffeine and alcohol--all of which can cause calcium depletion from bones. Vegetarian Bone-Up provides 100 percent of the RDI for calcium in each serving. The vegan form of calcium utilized, calcium citrate, readily ionizes to facilitate absorption.
The connection between calcium and bone-health is solid enough that the FDA has certified an approved health claim in relation to osteoporosis: "adequate calcium as part of a healthful diet, along with physical activity, may reduce the risk of osteoporosis in later life." But although calcium is a critical component of bone-tissue it is far from the only one.
Beyond Calcium
Magnesium (Mg), another under-consumed mineral, is necessary for skeletal health with 60 percent of bodily stores found in bone. Women with failing bone health tend to show diminished magnesium levels. Mg influences the secretion of parathyroid hormone (PTH), a critical regulator of calcium homeostasis affecting bone turnover. Mg is also necessary for the hydroxylation of dietary vitamin D, a process that converts it into the bioactive form called calcitriol.*
Vitamin D helps regulate the absorption and excretion of calcium and phosphorous, necessary elements for producing bone-mineral, hydroxyapatite. It also stimulates the synthesis of osteocalcin--a protein directly involved in bone mineralization and calcium homeostasis. Numerous studies have shown that vitamin D intake promotes balanced remodeling and strong bone-building from childhood through senescence.*
Vitamin K is essential for the carboxylation (i.e. activation) of specific bone proteins needed for building bone. Vitamin K also discourages unwanted calcium deposition in arteries. Vitamin K2, especially as menaquinone-7 (MK-7), is the more bioavailable form of vitamin K. K2 has a significantly longer biological half-life, remaining in circulation much longer than vitamin K1. MK-7 is the type of vitamin K found in natto, a fermented soybean product.
Zinc and manganese are present in small quantities in bone and help maintain the activity of bone-building cells, osteoblasts.* Vitamin C helps form collagen, the connective tissue that makes-up about 1/3 the weight of bone and imparts flexibility and durability. In addition, the enzyme responsible for further strengthening (i.e. cross-linking) collagen-fibers requires copper. Boron has been shown to reduce urinary losses of calcium and magnesium when daily intake reaches 3mg/day. Finally, potassium helps support alkalization of the body so it is less apt to dissolve bone to neutralize an overly acidic systemic pH.*
Living Formula for a Living Skeleton
The Original Bone-Up was first introduced over twenty years ago, but similar to your bones Bone-Up remains alive and dynamic. As bone research uncovers additional insights about bone health, the entire Bone-Up family of products is updated to reflect those advances. Often imitated, the Bone-Up family remains the tried and trusted leader for bone health.*
Health Claim: In conjunction with regular, weight-bearing exercise and a healthy diet, calcium helps teen and young adult women build bone mass and maintain bone health, and may reduce their risk of osteoporosis later in life.* Daily calcium intake above 2,000 mg is not likely to provide additional benefit. Adequate calcium intake is also linked to reduced osteoporosis by slowing bone loss in older men and women.*
About Jarrow Formulas
Jarrow Formulas' complete line of over 350 nutritional products includes vitamins, minerals, probiotics, standardized herbal concentrates, amino acids, enzymes and enteral nutrition products. Customers can be assured of purity, value and potency when choosing these products.
What's in the Box
Jarrow Formulas Bone-Up Vegetarian, 120 Tablets.
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